Depression (major depressive disorder) is a common but serious medical condition that affects how you feel, think, and handle daily activities. While it causes persistent sadness and loss of interest in previously enjoyed activities, the good news is depression is highly treatable with professional help.

Clinical depression involves distinct periods of significant mood changes, altered thought patterns, and reduced motivation lasting at least two weeks. These changes often include overwhelming negative thoughts, feelings of hopelessness, and difficulty with concentration and decision-making.